Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethohexadiol SCHEMBL2442063 | 0.84 | LMNA (0.70) | LMNAALDH1A1CYP3A4TSHRTDP1 | |
| Ethohexadiol SCHEMBL27697531 | 0.78 | LMNA (0.79) | LMNAALDH1A1CYP3A4TSHRHSD17B10 | |
| Ethohexadiol SCHEMBL10901986 | 0.77 | LMNA (0.70) | LMNAALDH1A1CYP3A4TSHR | |
| Ethohexadiol SCHEMBL28084564 | 0.77 | LMNA (0.76) | LMNAALDH1A1CYP3A4TSHRHSD17B10 | |
| Ethohexadiol SCHEMBL8675214 | 0.76 | LMNA (0.83) | LMNAALDH1A1CYP3A4TSHRTDP1 | |
| Ethohexadiol SCHEMBL10454295 | 0.76 | LMNA (0.83) | LMNAALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL22122578 | 0.76 | LMNA (0.74) | LMNAALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL3627525 | 0.76 | LMNA (0.74) | LMNAALDH1A1CYP3A4TSHRTDP1 | |
| Ethohexadiol SCHEMBL6282991 | 0.76 | LMNA (1.00) | LMNAALDH1A1CYP3A4TSHRTDP1 | |
| Ethohexadiol SCHEMBL38007 | 0.76 | LMNA (1.00) | LMNAALDH1A1CYP3A4TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450411-B2 | Curable composition having a silane-modified reactive thinner | HENKEL AG & CO. KGAA (DE) | 2013-05-28 | — | — | US | disclosed |
| US-20120108730-A1 | CURABLE COMPOSITION HAVING A SILANE-MODIFIED REACTIVE THINNER | HENKEL AG & CO. KGAA (DE) | 2012-05-03 | — | — | US | disclosed |
| US-8067508-B2 | Compositions consisting of partially silyl-terminated polymers | HENKEL AG & CO. KGAA (DE) | 2011-11-29 | — | — | US | disclosed |
| US-20100081757-A1 | COMPOSITIONS CONSISTING OF PARTIALLY SILYL-TERMINATED POLYMERS | HENKEL AG & CO. KGAA (DE) | 2010-04-01 | — | — | US | disclosed |