SCHEMBL13626927

SCHEMBL13626927

Bc1ccc(B)c(N)c1N

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12657274 0.82 GAA (0.33) MAPT
SCHEMBL10278897 0.77
SCHEMBL15514664 0.70
SCHEMBL22087465 0.66
SCHEMBL20255293 0.66 CD44 (0.39) MEN1MAPTKMT2A
SCHEMBL24156595 0.66 ALDH1A1 (0.33) MAPT
SCHEMBL21387083 0.66
SCHEMBL13772849 0.65
SCHEMBL14199223 0.63
SCHEMBL24326842 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009141386-A1 DERIVATIVES OF QUINOLINES AND QUINOXALINES AS PROTEIN TYROSINE KINASE INHIBITORS NOVARTIS AG (CH) 2009-11-26 WO disclosed