Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 4/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.44 |
| ▸ | BCR | P11274 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP4B1 | P13584 | 2/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.41 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.41 |
| ▸ | CYP2A7 | P20853 | 2/20 | 0.41 |
| ▸ | CYP3A7 | P24462 | 2/20 | 0.41 |
| ▸ | CYP2F1 | P24903 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126240 | 0.79 | ABL1 (0.44) | ABL1ABCB1BCRGAAMAPT | |
| SCHEMBL31648024 | 0.74 | ABL1 (0.43) | ABL1ABCB1BCRGAAMAPT | |
| SCHEMBL27935580 | 0.72 | ABL1 (0.48) | ABL1ABCB1BCRGAAMAPT | |
| SCHEMBL13626554 | 0.71 | ABL1 (0.45) | ABL1ABCB1BCRGAAMAPT | |
| SCHEMBL6011385 | 0.70 | ABL1 (0.47) | ABL1ABCB1BCRGAAMAPT | |
| SCHEMBL1165314 | 0.70 | FYN (0.52) | ABL1ABCB1BCRGAAMAPT | |
| SCHEMBL14212776 | 0.70 | MAOB (0.41) | ABL1ABCB1BCRGAAMAPT | |
| SCHEMBL5688059 | 0.69 | ABL1 (0.50) | ABL1ABCB1BCRGAAMAPT | |
| SCHEMBL31648381 | 0.68 | FGFR1 (0.55) | ABL1ABCB1BCRGAAMAPT | |
| SCHEMBL6572399 | 0.67 | ABL1 (0.47) | ABL1ABCB1BCRGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141386-A1 | DERIVATIVES OF QUINOLINES AND QUINOXALINES AS PROTEIN TYROSINE KINASE INHIBITORS | NOVARTIS AG (CH) | 2009-11-26 | — | — | WO | disclosed |