SCHEMBL13627027

SCHEMBL13627027

Cc1cc(C)c(OPOc2cccnc2)c(-c2cc(C)cc(C)c2OP(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.32
TP53 P04637 1/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
LMNA P02545 3/20 0.31
TDP1 Q9NUW8 1/20 0.31
CYP11B1 P15538 2/20 0.31
CYP11B2 P19099 2/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13627014 0.85 NPSR1 (0.33)
SCHEMBL14520768 0.80 NPC1 (0.32) NPC1TP53MAPTRAB9ASMN1; SMN2
SCHEMBL13199356 0.78 NPSR1 (0.35) MAPTLMNATSHR
SCHEMBL13627016 0.75 NPSR1 (0.31)
SCHEMBL2693261 0.71 CYP1A2 (0.36) MAPTLMNATDP1TSHR
SCHEMBL28567915 0.69 NPSR1 (0.40) MAPTSMN1; SMN2LMNATDP1TSHR
SCHEMBL13325298 0.68 MAPT (0.31) MAPT
SCHEMBL2603177 0.65 MAPT (0.30) MAPT
SCHEMBL14452692 0.64 KIF11 (0.36) NPC1TP53MAPTRAB9ASMN1; SMN2
SCHEMBL13593516 0.64 MAPT (0.30) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7615645-B2 Method for the continuous production of aldehydes BASF AKTIENGESELLSCHAFT (DE) 2009-11-10 US disclosed
US-20070004939-A1 Method for the continuous production of aldehydes VOLLAND MARTIN 2007-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070004939-A1 Method for the continuous production of aldehydes HRH4, HRH2, HRH3 NPC1 2155/4885TP53 2967/4885MAPT 4835/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.