SCHEMBL1362703

SCHEMBL1362703

Nc1cc(Br)ccc1C(=O)c1ccccc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.77
POLB P06746 1/20 0.77
GAA P10253 3/20 0.61
NPC1 O15118 2/20 0.53
MAPK1 P28482 2/20 0.53
HTT P42858 1/20 0.53
AKR1C3 P42330 1/20 0.51
PTGDR2 Q9Y5Y4 1/20 0.51
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
KDM4E B2RXH2 2/20 0.50
GLA P06280 2/20 0.50
ALDH1A1 P00352 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
ADORA2A P29274 1/20 0.50
CASP1 P29466 1/20 0.50
RAB9A P51151 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
USP2 O75604 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5484360 0.89 MAPT (0.61) MAPTPOLBGAANPC1MAPK1
SCHEMBL26738 0.87 MAPT (1.00) MAPTPOLBGAANPC1MAPK1
SCHEMBL29979531 0.87 MAPT (1.00) MAPTPOLBGAANPC1MAPK1
SCHEMBL8033801 0.82 MAPT (0.72) MAPTPOLBGAAMAPK1HTT
SCHEMBL1128877 0.82 MAPT (0.62) MAPTPOLBGAANPC1MAPK1
SCHEMBL29530940 0.81 MAPT (0.66) MAPTPOLBGAAMAPK1HTT
SCHEMBL29530480 0.81 MAPT (0.66) MAPTPOLBGAAMAPK1HTT
SCHEMBL3179244 0.81 MAPT (0.66) MAPTPOLBGAAMAPK1HTT
SCHEMBL9267999 0.81 MAPT (0.66) MAPTPOLBGAAMAPK1HTT
SCHEMBL28498875 0.81 MAPT (0.53) MAPTPOLBGAANPC1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119098205-A Nitrogen-doped porous carbon-loaded cobalt monoatomic catalyst and preparation method and application thereof 南京理工大学 2024-12-10 CN claimed
CN-118667159-A High-adhesion polyimide positive electrode binder and preparation method and application thereof 浙江中科玖源新材料有限公司 2024-09-20 CN claimed
CN-118420915-A Epoxy group modified polyamide imide binder and preparation method thereof 浙江中科玖源新材料有限公司 2024-08-02 CN claimed
CN-117164855-A High-cohesiveness branched polyimide polymer and preparation method thereof 江苏环峰电工材料有限公司 2023-12-05 CN claimed
EP-2613819-B2 LUBRICIOUS COATINGS FOR MEDICAL DEVICES BIOINTERACTIONS LTD (GB) 2020-11-25 EP claimed
US-12247040-B2 Iridium complex compound MITSUBISHI CHEMICAL CORPORATION (JP) 2025-03-11 US disclosed
CN-119504579-A Method for promoting catalytic synthesis of quinoline derivative by using p-toluenesulfonic acid as ligand and titanocene dichloride 宁夏师范大学 2025-02-25 CN disclosed
CN-119098205-A Nitrogen-doped porous carbon-loaded cobalt monoatomic catalyst and preparation method and application thereof 南京理工大学 2024-12-10 CN disclosed
EP-3909963-B1 IRIDIUM COMPLEX COMPOUND MITSUBISHI CHEM CORP (JP) 2024-10-30 EP disclosed
CN-118667159-A High-adhesion polyimide positive electrode binder and preparation method and application thereof 浙江中科玖源新材料有限公司 2024-09-20 CN disclosed
CN-118420915-A Epoxy group modified polyamide imide binder and preparation method thereof 浙江中科玖源新材料有限公司 2024-08-02 CN disclosed
CN-113698308-B Synthesis method of bromfenac sodium 山东辰龙药业有限公司 2024-06-21 CN disclosed
EP-0530994-A1 Quinazoline derivatives as inhibitors of HIV reverse transcriptase MERCK & CO. INC. (US) 1993-03-10 EP disclosed
EP-0076017-B1 PHENYL SUBSTITUTED PYRIDO(1,4)BENZODIAZEPINES AND INTERMEDIATES THEREFOR A.H. ROBINS COMPANY, INCORPORATED (US) 1990-08-16 EP disclosed
US-4556667-A (2-((AMINOPYRIDINYL)AMINO)PHENYL)ARYLMETHANONE INTERMEDIATES A. H. ROBINS COMPANY, INCORPORATED (US) 1985-12-03 US disclosed
US-4519937-A DOPED UNITS OF A FUSED NITROGEN-CONTAINING UNSATURATED HETEROCYCLIC RING CHEVRON RESEARCH COMPANY (US) 1985-05-28 US disclosed
US-4519938-A TRACTABLE, DOPED HETEROCYCLIC RINGS CHEVRON RESEARCH COMPANY (US) 1985-05-28 US disclosed
US-4495183-A ANTIULCER AGENTS- GASTROLINTESTINAL DISORDERS A. H. ROBINS COMPANY, INCORPORATED (US) 1985-01-22 US disclosed
US-4447361-A ANTIDEPRESSANT A. H. ROBINS COMPANY, INC. (US) 1984-05-08 US disclosed
EP-0076017-A2 Phenyl substituted pyrido(1,4)benzodiazepines and intermediates therefor A.H. ROBINS COMPANY, INCORPORATED (US) 1983-04-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12247040-B2 Iridium complex compound IPO5, CXCR5, PRMT5 MAPT 3004/4885POLB 2660/4885GAA 4636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.