Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.72 |
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.58 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8037904 | 0.93 | MAPT (0.69) | MAPTGAAPOLBALDH1A1AKR1C3 | |
| SCHEMBL12648642 | 0.87 | IDO1 (0.71) | MAPTGAAPOLBALDH1A1AKR1C3 | |
| SCHEMBL5537008 | 0.86 | MAPT (0.60) | MAPTGAAPOLBALDH1A1AKR1C3 | |
| SCHEMBL3179244 | 0.86 | MAPT (0.66) | MAPTGAAPOLBALDH1A1AKR1C3 | |
| SCHEMBL11215128 | 0.86 | MAPT (0.60) | MAPTGAAPOLBALDH1A1AKR1C3 | |
| SCHEMBL686613 | 0.86 | MAPT (0.60) | MAPTGAAPOLBALDH1A1AKR1C3 | |
| SCHEMBL29530480 | 0.86 | MAPT (0.66) | MAPTGAAPOLBALDH1A1AKR1C3 | |
| SCHEMBL11117347 | 0.86 | MAPT (0.60) | MAPTGAAPOLBALDH1A1AKR1C3 | |
| SCHEMBL21573930 | 0.86 | MAPT (0.60) | MAPTGAAPOLBALDH1A1AKR1C3 | |
| SCHEMBL9061252 | 0.85 | ALDH1A1 (0.58) | MAPTGAAPOLBALDH1A1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4000187-A | THERMAL STABILITY, COATINGS, CAST FILMS | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1976-12-28 | — | — | US | claimed |
| US-9809594-B2 | Non-fullerene electron acceptors for organic photovoltaic devices | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2017-11-07 | — | — | US | disclosed |
| US-9809594-B2 | Non-fullerene electron acceptors for organic photovoltaic devices | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2017-11-07 | — | — | US | disclosed |
| US-9809594-B2 | Non-fullerene electron acceptors for organic photovoltaic devices | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2017-11-07 | — | — | US | disclosed |
| US-20170057962-A1 | NON-FULLERENE ELECTRON ACCEPTORS FOR ORGANIC PHOTOVOLTAIC DEVICES | UNIVERSITY OF WASHINGTON (US) | 2017-03-02 | — | — | US | disclosed |
| US-20170057962-A1 | NON-FULLERENE ELECTRON ACCEPTORS FOR ORGANIC PHOTOVOLTAIC DEVICES | UNIVERSITY OF WASHINGTON (US) | 2017-03-02 | — | — | US | disclosed |
| US-20170057962-A1 | NON-FULLERENE ELECTRON ACCEPTORS FOR ORGANIC PHOTOVOLTAIC DEVICES | UNIVERSITY OF WASHINGTON (US) | 2017-03-02 | — | — | US | disclosed |
| US-9508937-B2 | Acenaphthylene imide-derived semiconductors | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2016-11-29 | — | — | US | disclosed |
| US-9508937-B2 | Acenaphthylene imide-derived semiconductors | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2016-11-29 | — | — | US | disclosed |
| US-9508937-B2 | Acenaphthylene imide-derived semiconductors | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2016-11-29 | — | — | US | disclosed |
| US-5814833-A | OPTICAL AND ELECTRONIC POLYMERS FOR ELECTRONICS, PHOTONICS AND OPTOELECTRONICS APPLICATIONS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1998-09-29 | — | — | US | disclosed |
| US-5723573-A | ACETYLENIC END GROUPS | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1998-03-03 | — | — | US | disclosed |
| US-5597890-A | ENHANCED LUMINESCENCE AND PHOTOGENERATION OF CHARGE CARRIERS AND QUANTUM EFFICIENCY USING N-HETEROCYCLE AROMATIC RESINS AND AN ELECTRON DONOR OR ACCEPTOR; OPTOELECTRONICS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-01-28 | — | — | US | disclosed |
| WO-1995012628-A1 | CONJUGATED POLYMER EXCIPLEXES AND APPLICATIONS THEREOF | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-05-11 | — | — | WO | disclosed |
| WO-1994004592-A1 | PHOTOCONDUCTIVE POLYMERS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1994-03-03 | — | — | WO | disclosed |
| EP-0444142-A4 | POLYQUINOLINE COPOLYMERS | — | 1991-10-16 | — | — | EP | disclosed |
| EP-0444142-A1 | POLYQUINOLINE COPOLYMERS | HITACHI CHEMICAL CO., LTD. (JP) | 1991-09-04 | — | — | EP | disclosed |
| US-5017677-A | Molding materials, laminates, adhesives, films and fibers | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1991-05-21 | — | — | US | disclosed |
| WO-1990005754-A1 | POLYQUINOLINE COPOLYMERS | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1990-05-31 | — | — | WO | disclosed |
| US-4000187-A | THERMAL STABILITY, COATINGS, CAST FILMS | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1976-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170057962-A1 | NON-FULLERENE ELECTRON ACCEPTORS FOR ORGANIC PHOTOVOLTAIC DEVICES | VDAC1, SLC19A1, SLC46A1 | MAPT 1574/4885GAA 4216/4885POLB 1942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.