Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13356526 | 0.90 | HTT (0.35) | LMNAALDH1A1THRBTSHRMAPK1 | |
| SCHEMBL13306214 | 0.74 | HTT (0.46) | LMNAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL13356459 | 0.74 | CNR1 (0.34) | LMNAALDH1A1THRBTSHRMAPK1 | |
| SCHEMBL13515698 | 0.74 | ALDH1A1 (0.34) | LMNAALDH1A1THRBTSHRMAPK1 | |
| SCHEMBL13306213 | 0.71 | HTT (0.34) | LMNAALDH1A1THRBTSHRMAPK1 | |
| SCHEMBL13356460 | 0.69 | MEN1 (0.39) | LMNAALDH1A1MAPK1MAPTMEN1 | |
| SCHEMBL13515633 | 0.69 | SMN1; SMN2 (0.42) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL1076637 | 0.69 | ALDH1A1 (0.37) | LMNAALDH1A1THRBTSHRMAPK1 | |
| SCHEMBL12479809 | 0.69 | HTT (0.55) | LMNAALDH1A1MEN1KMT2AHTT | |
| SCHEMBL13356658 | 0.68 | HTT (0.36) | ALDH1A1MEN1KMT2AHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140451-A1 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING SAID COMPOUNDS, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2009-11-19 | — | — | WO | disclosed |