Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 16/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 15/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 15/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 14/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 14/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 14/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 14/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 14/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 13/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 13/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 13/20 | 0.50 |
| ▸ | NCOR1 | O75376 | 2/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836588 | 0.83 | EPHX2 (0.54) | HDAC6HDAC1HDAC8HDAC5HDAC3 | |
| SCHEMBL28571572 | 0.82 | TP53 (0.42) | HDAC6HDAC1HDAC8HDAC11HDAC3 | |
| SCHEMBL26190451 | 0.82 | TP53 (0.42) | HDAC6HDAC1HDAC8HDAC11HDAC3 | |
| SCHEMBL30985368 | 0.81 | TP53 (0.43) | HDAC6HDAC1HDAC8HDAC11HDAC3 | |
| SCHEMBL26190346 | 0.81 | SMN1; SMN2 (0.41) | HDAC6HDAC1HDAC8HDAC11HDAC3 | |
| SCHEMBL30985338 | 0.81 | TP53 (0.43) | HDAC6HDAC1HDAC8HDAC11HDAC3 | |
| SCHEMBL30985315 | 0.81 | TP53 (0.43) | HDAC6HDAC1HDAC8HDAC11HDAC3 | |
| SCHEMBL13771295 | 0.80 | TP53 (0.42) | HDAC6HDAC1HDAC8HDAC11HDAC3 | |
| SCHEMBL13771143 | 0.80 | TP53 (0.42) | HDAC6HDAC1HDAC8HDAC11HDAC3 | |
| SCHEMBL1491596 | 0.80 | TP53 (0.42) | HDAC6HDAC1HDAC8HDAC11HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291978-A1 | Enzyme Inhibitors | CHROMA THERAPEUTICS LTD. (GB) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291978-A1 | Enzyme Inhibitors | HAT1, NR2E1, NR2C2 | CYP3A4 902/4885KCNH2 3160/4885CYP2C9 2059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.