Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1349427 | 0.89 | CA12 (0.44) | EPHX2EPHX1MGLLNPC1RAB9A | |
| SCHEMBL25841424 | 0.85 | MGLL (0.44) | EPHX2MGLL | |
| SCHEMBL5020595 | 0.83 | HDAC1 (0.48) | EPHX1HDAC1HDAC8MGLL | |
| SCHEMBL13627289 | 0.83 | CYP3A4 (0.53) | EPHX2HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL31051163 | 0.82 | KMT2A (0.50) | EPHX2MGLL | |
| SCHEMBL31051162 | 0.82 | MGLL (0.42) | EPHX2EPHX1MGLL | |
| SCHEMBL26186293 | 0.81 | ALDH1A1 (0.43) | EPHX2MGLLNPC1RAB9A | |
| SCHEMBL26190346 | 0.80 | SMN1; SMN2 (0.41) | EPHX2EPHX1HDAC1HDAC3HDAC2 | |
| SCHEMBL26190451 | 0.79 | TP53 (0.42) | EPHX2EPHX1HDAC1HDAC3HDAC2 | |
| SCHEMBL28571572 | 0.79 | TP53 (0.42) | EPHX2EPHX1HDAC1HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200377-B1 | HYDROXAMATES | SQUIBB & SONS INC (US) | 1991-10-09 | — | — | EP | disclosed |
| EP-0200377-A2 | Hydroxamates | E.R. Squibb & Sons, Inc. (US) | 1986-11-05 | — | — | EP | disclosed |
| US-4604407-A | Hydroxamates | E. R. SQUIBB & SONS, INC. (US) | 1986-08-05 | — | — | US | disclosed |