Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.40 |
| ▸ | RPA1 | P27694 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2914583 | 0.89 | MGLL (0.44) | MGLLSCDSCD5RPA1PTGS1 | |
| SCHEMBL13212909 | 0.88 | MGLL (0.44) | MGLLSCDSCD5RPA1PTGS1 | |
| Hydrochloric Acid SCHEMBL2918326 | 0.88 | MGLL (0.43) | MGLLSCDSCD5RPA1PTGS1 | |
| SCHEMBL2919458 | 0.87 | MGLL (0.46) | MGLLSCDSCD5RPA1PTGS1 | |
| SCHEMBL2921275 | 0.87 | MGLL (0.45) | MGLLSCDSCD5RPA1PTGS1 | |
| SCHEMBL2912065 | 0.86 | MGLL (0.45) | MGLLSCDSCD5RPA1PTGS1 | |
| SCHEMBL13637496 | 0.85 | MGLL (0.44) | MGLLSCDSCD5RPA1PTGS1 | |
| SCHEMBL2911147 | 0.83 | PTGS1 (0.45) | MGLLSCDSCD5RPA1PTGS1 | |
| SCHEMBL13637495 | 0.83 | HPGD (0.54) | MGLLSCDSCD5RPA1PTGS1 | |
| SCHEMBL2917722 | 0.81 | SCD (0.44) | MGLLSCDSCD5RPA1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622471-B2 | Pyrazole derivatives having a pyridazine and pyridine functionality | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-11-24 | — | — | US | disclosed |
| US-7622471-B2 | Pyrazole derivatives having a pyridazine and pyridine functionality | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-11-24 | — | — | US | disclosed |