Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 10/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CCKAR | P32238 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2917069 | 0.92 | MGLL (0.57) | MGLLKCNH2MALT1PTGS2MEN1 | |
| SCHEMBL2911969 | 0.92 | MGLL (0.57) | MGLLKCNH2MALT1PTGS2MEN1 | |
| SCHEMBL2920388 | 0.91 | MALT1 (0.61) | MGLLKCNH2MALT1PTGS2MEN1 | |
| SCHEMBL13637494 | 0.91 | MGLL (0.56) | MGLLKCNH2MALT1PTGS2MEN1 | |
| SCHEMBL2911623 | 0.91 | MGLL (0.56) | MGLLKCNH2MALT1PTGS2MEN1 | |
| SCHEMBL2917284 | 0.91 | MGLL (0.63) | MGLLKCNH2MALT1PTGS2CCKAR | |
| SCHEMBL2914856 | 0.90 | MGLL (0.54) | MGLLKCNH2MALT1PTGS2MEN1 | |
| SCHEMBL2910679 | 0.89 | MGLL (0.53) | MGLLKCNH2MALT1PTGS2MEN1 | |
| SCHEMBL5268680 | 0.89 | MGLL (0.52) | MGLLKCNH2MALT1PTGS2CFTR | |
| SCHEMBL5265747 | 0.87 | MGLL (0.51) | MGLLKCNH2MALT1PTGS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622471-B2 | Pyrazole derivatives having a pyridazine and pyridine functionality | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-11-24 | — | — | US | disclosed |
| US-7622471-B2 | Pyrazole derivatives having a pyridazine and pyridine functionality | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-11-24 | — | — | US | disclosed |