Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.46 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21213964 | 0.86 | ALDH1A1 (0.61) | HTTHRH3KDM4EGAAALDH1A1 | |
| SCHEMBL1286688 | 0.84 | HTT (0.75) | HTTHRH3KDM4EGAAALDH1A1 | |
| SCHEMBL1243301 | 0.82 | HTT (1.00) | HTTHRH3KDM4EGAAALDH1A1 | |
| SCHEMBL25062750 | 0.81 | HTT (0.71) | HTTHRH3KDM4EGAAALDH1A1 | |
| SCHEMBL4136038 | 0.81 | HTT (0.75) | HTTHRH3KDM4EGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL3500894 | 0.81 | HTT (0.97) | HTTHRH3KDM4EGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL3500984 | 0.79 | HTT (0.73) | HTTHRH3KDM4EGAAALDH1A1 | |
| SCHEMBL5095146 | 0.79 | KMT2A (0.67) | KDM4EALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL3501938 | 0.78 | HTT (0.66) | HTTHRH3KDM4EGAAALDH1A1 | |
| SCHEMBL25062318 | 0.76 | HTT (0.63) | HTTHRH3KDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7619092-B2 | Piperidine compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-11-17 | — | — | US | disclosed |
| US-7619092-B2 | Piperidine compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-11-17 | — | — | US | disclosed |