Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9404693 | 0.88 | MAOB (0.48) | MAOBALDH1A1HTTTHRBMEN1 | |
| SCHEMBL719824 | 0.87 | MAOB (0.56) | MAOBALDH1A1HTTMEN1KMT2A | |
| SCHEMBL11025540 | 0.86 | MAOB (0.46) | MAOBALDH1A1HTTMEN1KMT2A | |
| SCHEMBL997591 | 0.85 | THRB (0.54) | ALDH1A1HTTTHRBSMN1; SMN2LMNA | |
| SCHEMBL15320876 | 0.81 | MAOB (0.46) | MAOBALDH1A1HTTMEN1KMT2A | |
| SCHEMBL15294336 | 0.80 | KMT2A (0.39) | MAOBALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL15294327 | 0.80 | KMT2A (0.39) | MAOBALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL15294333 | 0.80 | KMT2A (0.39) | MAOBALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL8964981 | 0.80 | MAOB (0.45) | MAOBALDH1A1HTTTHRBMEN1 | |
| SCHEMBL11025521 | 0.79 | MAOB (0.41) | MAOBALDH1A1HTTTHRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612153-B2 | conjugate polymer drugs; endcapped polyethers; nontoxic, biocompatible, non-immunogenic, soluble in water and other solvents | INTEZYNE TECHNOLOGIES, INC. (US) | 2009-11-03 | — | — | US | disclosed |