Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015395 | 0.98 | MAPT (0.37) | MAPTHTTMEN1THRBKMT2A | |
| SCHEMBL23015153 | 0.95 | MAPT (0.40) | MAPTHTTMEN1THRBKMT2A | |
| SCHEMBL14480297 | 0.95 | MAPT (0.40) | MAPTHTTMEN1THRBKMT2A | |
| SCHEMBL15775433 | 0.91 | — | — | |
| SCHEMBL23567273 | 0.89 | USP2 (0.31) | MAPTHTTMEN1THRBKMT2A | |
| SCHEMBL19233495 | 0.88 | MAPT (0.37) | MAPTHTTMEN1THRBKMT2A | |
| SCHEMBL23567314 | 0.87 | MAPT (0.33) | MAPTHTTMEN1THRBKMT2A | |
| SCHEMBL23567248 | 0.87 | MAPT (0.33) | MAPTHTTMEN1THRBKMT2A | |
| SCHEMBL23567235 | 0.87 | MAPT (0.33) | MAPTHTTMEN1THRBKMT2A | |
| SCHEMBL23567321 | 0.87 | MAPT (0.33) | MAPTHTTMEN1THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612153-B2 | conjugate polymer drugs; endcapped polyethers; nontoxic, biocompatible, non-immunogenic, soluble in water and other solvents | INTEZYNE TECHNOLOGIES, INC. (US) | 2009-11-03 | — | — | US | disclosed |