⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015395 | 0.93 | MAPT (0.37) | — | |
| SCHEMBL23567232 | 0.91 | TSHR (0.30) | — | |
| SCHEMBL14480297 | 0.91 | MAPT (0.40) | — | |
| SCHEMBL23015153 | 0.91 | MAPT (0.40) | — | |
| SCHEMBL13627809 | 0.91 | MAPT (0.40) | — | |
| SCHEMBL25755554 | 0.90 | TSHR (0.48) | — | |
| SCHEMBL4391948 | 0.87 | TSHR (0.36) | — | |
| SCHEMBL1453392 | 0.84 | — | — | |
| SCHEMBL23567273 | 0.84 | USP2 (0.31) | — | |
| SCHEMBL5325109 | 0.83 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158157-A1 | POTENT AND SELECTIVE DEGRADERS OF ALK | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-05-25 | — | — | US | disclosed |
| US-20230149551-A1 | ARGININE METHYLTRANSFERASE 5 (PRMT5) DEGRADERS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-05-18 | — | — | US | disclosed |
| US-10023514-B2 | Odorants of the violet type | FIRMENICH SA (CH) | 2018-07-17 | — | — | US | disclosed |
| EP-2928995-B1 | ODORANTS OF THE VIOLET TYPE | FIRMENICH & CIE (CH) | 2016-08-24 | — | — | EP | disclosed |
| US-20150315516-A1 | ODORANTS OF THE VIOLET TYPE | FIRMENICH SA (CH) | 2015-11-05 | — | — | US | disclosed |
| EP-2928995-A1 | ODORANTS OF THE VIOLET TYPE | Firmenich SA (CH) | 2015-10-14 | — | — | EP | disclosed |
| WO-2014086608-A1 | ODORANTS OF THE VIOLET TYPE | FIRMENICH SA (CH) | 2014-06-12 | — | — | WO | disclosed |