Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13628073 | 1.00 | NR1H2 (0.43) | NR1H2PTPN1PDE4BNR1H3ALDH1A1 | |
| SCHEMBL13628062 | 1.00 | NR1H2 (0.43) | NR1H2PTPN1PDE4BNR1H3ALDH1A1 | |
| SCHEMBL13628034 | 0.85 | NR1H2 (0.37) | NR1H2PTPN1PDE4BNR1H3ALDH1A1 | |
| SCHEMBL13628497 | 0.85 | MAPT (0.42) | NR1H2PTPN1PDE4BNR1H3ALDH1A1 | |
| SCHEMBL3077286 | 0.82 | NR1H2 (0.41) | NR1H2PTPN1PDE4BNR1H3ALDH1A1 | |
| SCHEMBL2912061 | 0.82 | NR1H2 (0.41) | NR1H2PTPN1PDE4BNR1H3ALDH1A1 | |
| SCHEMBL12219940 | 0.82 | NR1H2 (0.41) | NR1H2PTPN1PDE4BNR1H3ALDH1A1 | |
| SCHEMBL4338373 | 0.82 | NR1H2 (0.41) | NR1H2PTPN1PDE4BNR1H3ALDH1A1 | |
| SCHEMBL2913738 | 0.82 | NR1H2 (0.41) | NR1H2PTPN1PDE4BNR1H3ALDH1A1 | |
| SCHEMBL3083078 | 0.82 | NR1H2 (0.41) | NR1H2PTPN1PDE4BNR1H3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622585-B2 | Phenylglycinamide derivatives useful as anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-11-24 | — | — | US | disclosed |