Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15268057 | 0.85 | NR1H2 (0.42) | MAPTLMNAALDH1A1DRD2GHSR | |
| SCHEMBL13628062 | 0.85 | NR1H2 (0.43) | MAPTLMNAALDH1A1NR1H2NR1H3 | |
| SCHEMBL13627820 | 0.85 | NR1H2 (0.43) | MAPTLMNAALDH1A1NR1H2NR1H3 | |
| SCHEMBL13628073 | 0.85 | NR1H2 (0.43) | MAPTLMNAALDH1A1NR1H2NR1H3 | |
| SCHEMBL3077165 | 0.83 | MAPT (0.40) | MAPTLMNAALDH1A1DRD2GHSR | |
| SCHEMBL11351128 | 0.83 | MAPT (0.40) | MAPTLMNAALDH1A1DRD2GHSR | |
| SCHEMBL12219935 | 0.83 | MAPT (0.40) | MAPTLMNAALDH1A1DRD2GHSR | |
| SCHEMBL3085742 | 0.83 | MAPT (0.40) | MAPTLMNAALDH1A1DRD2GHSR | |
| SCHEMBL3092891 | 0.83 | MAPT (0.40) | MAPTLMNAALDH1A1DRD2GHSR | |
| SCHEMBL11351145 | 0.83 | MAPT (0.40) | MAPTLMNAALDH1A1DRD2GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622585-B2 | Phenylglycinamide derivatives useful as anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-11-24 | — | — | US | disclosed |