SCHEMBL13628530

SCHEMBL13628530

C=C(C)[C@@H]1CC[C@]2(C(=O)NCCc3cccc(C(=O)NCc4ccc(C(=O)N[C@@H](C(=O)O)[C@H](C)N5CCN(C)CC5)cc4)c3)CC[C@]3(C)C(CCC4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@]43C)C12

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ RORC P51449 18/20 0.53
▸ TRPV1 Q8NER1 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13628528 0.94 TRPV1 (0.51) RORCTRPV1
SCHEMBL13628522 0.92 TRPV1 (0.56) RORCTRPV1
SCHEMBL13628500 0.92 TRPV1 (0.56) RORCTRPV1
SCHEMBL13628502 0.88 TRPV1 (0.58) RORCTRPV1
SCHEMBL13628509 0.88 TRPV1 (0.58) RORCTRPV1
SCHEMBL13628546 0.88 TRPV1 (0.56) RORCTRPV1
SCHEMBL13628565 0.87 TRPV1 (0.64) RORCTRPV1
SCHEMBL13637694 0.87 TRPV1 (0.62) RORCTRPV1
SCHEMBL13628293 0.87 TRPV1 (0.62) RORCTRPV1
SCHEMBL13628467 0.86 TRPV1 (0.55) RORCTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090275583-A1 ANTIVIRAL COMPOUNDS AND USE THEREOF MYRIAD GENETICS, INCORPORATED (US) 2009-11-05 — — US disclosed
US-20090275583-A1 ANTIVIRAL COMPOUNDS AND USE THEREOF MYRIAD GENETICS, INCORPORATED (US) 2009-11-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090275583-A1 ANTIVIRAL COMPOUNDS AND USE THEREOF MAVS, ZC3HAV1, EIF2AK2 RORC 514/4885TRPV1 3411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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