Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12530835 | 0.79 | HRH1 (0.50) | CYP1A2ALDH1A1CYP2C19HRH3HRH1 | |
| SCHEMBL6859512 | 0.76 | HRH1 (0.55) | CYP1A2ALDH1A1CYP2C19HRH3HRH1 | |
| SCHEMBL7445422 | 0.76 | HRH1 (0.58) | CYP1A2ALDH1A1CYP2C19HRH3HRH1 | |
| SCHEMBL10240776 | 0.76 | CYP1A2 (0.57) | CYP1A2ALDH1A1CYP2C19HRH3HRH1 | |
| SCHEMBL29485637 | 0.73 | HRH1 (0.69) | CYP1A2ALDH1A1CYP2C19HRH3HRH1 | |
| SCHEMBL726512 | 0.73 | HRH1 (0.76) | CYP1A2ALDH1A1CYP2C19HRH3HRH1 | |
| SCHEMBL231470 | 0.73 | HRH1 (0.69) | CYP1A2ALDH1A1CYP2C19HRH3HRH1 | |
| SCHEMBL147199 | 0.73 | CYP3A4 (0.61) | CYP1A2ALDH1A1CYP2C19HRH3HRH1 | |
| SCHEMBL28601548 | 0.73 | HRH1 (0.55) | CYP1A2ALDH1A1CYP2C19HRH3HRH1 | |
| SCHEMBL12604331 | 0.73 | CYP1A2 (0.57) | CYP1A2ALDH1A1CYP2C19HRH3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612197-B2 | Reacting a nucleophil with OH group with an electrophil to form an adduct, reacting adduct with a reagent selected from oxidizing, sulfurizing or selenizing agents to produce hydroxy protected oligonucleotide, heating to deprotect hydroxy protecting group such as 2-(2-pyridyl)aminoethoxycarbonyl | The United States of America as repesented by the Secretary of the Department of Health and Human Services (US) | 2009-11-03 | — | — | US | disclosed |