SCHEMBL13628764

SCHEMBL13628764

Cc1ccc(-c2nnn[nH]2)[nH]1

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HMBS P08397 1/20 0.39
HPGDS O60760 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13628755 0.76
SCHEMBL13628761 0.71 CYP2A6 (0.40)
SCHEMBL12141823 0.69 HMBS (0.67) HMBS
SCHEMBL10054604 0.67 HMBS (0.62) HMBS
SCHEMBL1104622 0.67 HMBS (0.62) HMBS
SCHEMBL15788744 0.67 HMBS (0.62) HMBS
SCHEMBL12000745 0.67 HMBS (0.62) HMBS
SCHEMBL184092 0.67 DCUN1D1 (0.44)
SCHEMBL101638 0.67
SCHEMBL25246618 0.65 AURKA (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7612070-B2 Heterocyclic compounds as antiinflammatory agents and cyclooxygenase inhibitors CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2009-11-03 US disclosed