Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | SGK1 | O00141 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RRM1 | P23921 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13628746 | 0.87 | KMT2A (0.58) | KMT2AMEN1SGK1LMNAALOX15 | |
| SCHEMBL13628782 | 0.83 | KMT2A (0.54) | KMT2AMEN1SGK1LMNAALOX15 | |
| SCHEMBL13628724 | 0.82 | LMNA (0.56) | KMT2AMEN1SGK1LMNANPC1 | |
| SCHEMBL13628713 | 0.80 | SGK1 (0.64) | KMT2AMEN1SGK1LMNANPC1 | |
| SCHEMBL13628744 | 0.80 | MAPT (0.62) | KMT2AMEN1SGK1LMNANPC1 | |
| SCHEMBL13628754 | 0.78 | LMNA (0.63) | KMT2AMEN1SGK1LMNANPC1 | |
| SCHEMBL13628750 | 0.77 | LMNA (0.67) | KMT2AMEN1SGK1LMNANPC1 | |
| SCHEMBL13628774 | 0.77 | SGK1 (0.53) | KMT2AMEN1SGK1LMNANPC1 | |
| SCHEMBL13628735 | 0.77 | LMNA (0.76) | KMT2AMEN1SGK1LMNAMAPT | |
| SCHEMBL13628784 | 0.77 | KMT2A (0.54) | KMT2AMEN1SGK1LMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7619115-B2 | Ortho-substituted N'-benzylidene-(3-hydroxyphenyl)acethydrazides | MERCK PATENT GMBH (DE) | 2009-11-17 | — | — | US | disclosed |
| US-7619115-B2 | Ortho-substituted N'-benzylidene-(3-hydroxyphenyl)acethydrazides | MERCK PATENT GMBH (DE) | 2009-11-17 | — | — | US | disclosed |