SCHEMBL13628940

SCHEMBL13628940

CCNC(=O)OC1CC(C)(C)N(O)C(C)(C)C1

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.53
GAA P10253 4/20 0.43
HTT P42858 1/20 0.43
ALDH1A1 P00352 1/20 0.41
KMT2A Q03164 3/20 0.39
MEN1 O00255 1/20 0.39
BCHE P06276 7/20 0.38
KDM4E B2RXH2 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
TSHR P16473 2/20 0.32
ACHE P22303 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24372232 0.87 BCHE (0.49) EPHX1GAAHTTALDH1A1KMT2A
SCHEMBL4408314 0.84 BCHE (0.51) EPHX1GAAHTTBCHEACHE
SCHEMBL1138543 0.84 EPHX1 (0.50) EPHX1GAAHTTALDH1A1KMT2A
SCHEMBL8161429 0.84 GAA (0.41) EPHX1GAAHTTBCHEKDM4E
SCHEMBL24136469 0.81 MEN1 (0.41) EPHX1GAAHTTALDH1A1KMT2A
SCHEMBL13227472 0.81 GAA (0.46) EPHX1GAAHTTALDH1A1KMT2A
SCHEMBL3765199 0.80 GAA (0.50) GAAHTTALDH1A1KMT2AKDM4E
SCHEMBL272468 0.79 GAA (0.47) GAAHTTALDH1A1KMT2AMEN1
SCHEMBL29482620 0.78 EPHX2 (0.41) EPHX1GAAHTTKMT2ABCHE
SCHEMBL13819307 0.78 GAA (0.37) EPHX1GAAHTTKMT2ABCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090292044-A1 MODIFIED DIENE-BASED RUBBER AND RUBBER COMPOSITION CONTAINING THE SAME THE YOKOHAMA RUBBER CO., LTD. (JP) 2009-11-26 US disclosed
US-20080262147-A1 Modified by a nitroxide-free radical stable in the presence of oxygen at an ordinary temperature (a 2,2,6,6-tetramethyl piperidinyloxy derivative) and an organic peroxide crosslinking agent; improved cost efficiency; high tensile properties THE YOKOHAMA RUBBER CO., LTD. (JP) 2008-10-23 US disclosed