SCHEMBL24372232

SCHEMBL24372232

CCCNC(=O)OC1CC(C)(C)N(O)C(C)(C)C1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 4/20 0.49
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
ATM Q13315 1/20 0.41
GAA P10253 3/20 0.41
HTT P42858 1/20 0.41
EPHX1 P07099 1/20 0.39
KCNA3 P22001 3/20 0.37
CHRNB2 P17787 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA7 P36544 1/20 0.36
CHRNA4 P43681 1/20 0.36
KCNA2 P16389 1/20 0.35
KCNA1 Q09470 1/20 0.35
LIPE Q05469 1/20 0.35
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4408314 0.91 BCHE (0.51) BCHEGAAHTTEPHX1KCNA3
SCHEMBL8161429 0.88 GAA (0.41) BCHEGAAHTTEPHX1KDM4E
SCHEMBL13628940 0.87 EPHX1 (0.53) BCHEMEN1KMT2AL3MBTL1ALDH1A1
SCHEMBL24136469 0.85 MEN1 (0.41) BCHEMEN1KMT2AALDH1A1MAPT
SCHEMBL13819307 0.81 GAA (0.37) BCHEKMT2AGAAHTTEPHX1
SCHEMBL29482620 0.81 EPHX2 (0.41) BCHEKMT2AGAAHTTEPHX1
SCHEMBL9456357 0.79 BCHE (0.46) BCHEMEN1KMT2AL3MBTL1ALDH1A1
SCHEMBL17888048 0.79 GAA (0.51) BCHEGAAEPHX1KCNA3ACHE
SCHEMBL20928278 0.79 BCHE (0.49) BCHEMEN1KMT2AL3MBTL1ALDH1A1
Butane SCHEMBL10595891 0.79 GAA (0.43) MEN1KMT2AL3MBTL1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3988561-A1 PREPARATION AND USE OF REACTIVE OXYGEN SPECIES SCAVENGER XWPharma Ltd. (KY) 2022-04-27 EP disclosed