Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.61 |
| ▸ | MEN1 | O00255 | 10/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | CASP7 | P55210 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11970897 | 0.91 | MAPT (0.61) | MAPTKMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL13362016 | 0.84 | KMT2A (0.64) | MAPTKMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL11955042 | 0.81 | KMT2A (0.56) | MAPTKMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL31108179 | 0.79 | HTR1A (0.54) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL4323287 | 0.79 | HTR1A (0.54) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL10289639 | 0.75 | MAPT (0.55) | MAPTKMT2AMEN1SMN1; SMN2POLB | |
| Propane SCHEMBL28181810 | 0.74 | KDM4E (0.65) | SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL2515756 | 0.74 | MAPT (0.60) | MAPTKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL29292795 | 0.74 | KMT2A (0.62) | MAPTKMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL532789 | 0.74 | HTR1A (0.55) | MAPTKMT2AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8343636-B2 | Crosslinkable hole-transporting materials for organic light-emitting devices | UNIVERSITY OF WASHINGTON (US) | 2013-01-01 | — | — | US | disclosed |
| US-20090278445-A1 | CROSSLINKABLE HOLE-TRANSPORTING MATERIALS FOR ORGANIC LIGHT-EMITTING DEVICES | WASHINGTON, UNIVERSITY OF (US) | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090278445-A1 | CROSSLINKABLE HOLE-TRANSPORTING MATERIALS FOR ORGANIC LIGHT-EMITTING DEVICES | SUN2, HTT, SLC29A1 | MAPT 156/4885KMT2A 2704/4885MEN1 2670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.