Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 11/20 | 0.54 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | MPL | P40238 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CD40 | P25942 | 1/20 | 0.37 |
| ▸ | CD40LG | P29965 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10392594 | 0.89 | ENPP2 (0.47) | ENPP2PHLPP2MPLMEN1THRB | |
| SCHEMBL13615204 | 0.89 | ENPP2 (0.44) | ENPP2PHLPP2PTPN1MPLMEN1 | |
| SCHEMBL14645033 | 0.85 | PHLPP2 (0.64) | ENPP2PHLPP2PTPN1MEN1THRB | |
| SCHEMBL14647838 | 0.85 | ENPP2 (0.58) | ENPP2PHLPP2PTPN1CD40CD40LG | |
| SCHEMBL8124363 | 0.84 | CD40 (0.51) | ENPP2PHLPP2MPLMEN1THRB | |
| SCHEMBL8124361 | 0.84 | CD40 (0.51) | ENPP2PHLPP2MPLMEN1THRB | |
| SCHEMBL17284068 | 0.80 | ENPP2 (0.56) | ENPP2PHLPP2PTPN1MEN1THRB | |
| SCHEMBL11315827 | 0.79 | CD40 (0.45) | ENPP2PHLPP2MPLMEN1THRB | |
| SCHEMBL10625284 | 0.79 | ENPP2 (0.76) | ENPP2PHLPP2PTPN1MEN1THRB | |
| SCHEMBL10625271 | 0.79 | ENPP2 (0.73) | ENPP2PHLPP2PTPN1MEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275742-A1 | COLORING MATTER FOR ANISOTROPIC COLORING MATTER FILM, COMPOSITION COMPRISING SAID COLORING MATTER, ANISOTROPIC COLORING MATTER FILM, AND POLARIZING ELEMENT | MITSUBISHI CHEMICAL CORPORATION (JP) | 2009-11-05 | — | — | US | disclosed |