Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.49 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13629320 | 0.87 | SLC22A12 (0.54) | MEN1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13629773 | 0.85 | ALDH1A1 (0.57) | MEN1KMT2ASLC22A12ALDH1A1SMN1; SMN2 | |
| SCHEMBL13629311 | 0.84 | SLC22A12 (0.62) | CYP3A4CYP2C9SLC22A12HIF1ABRD4 | |
| SCHEMBL13629401 | 0.82 | ALDH1A1 (0.65) | MEN1LMNAKMT2ASLC22A12ALDH1A1 | |
| SCHEMBL13615078 | 0.79 | SLC22A12 (0.54) | MEN1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11220197 | 0.78 | MAPT (0.52) | MEN1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13629329 | 0.77 | ALDH1A1 (0.65) | LMNAMAPTALDH1A1TP53TDP1 | |
| SCHEMBL1040044 | 0.77 | ALDH1A1 (0.59) | MEN1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13629414 | 0.77 | MAPT (0.55) | MEN1LMNAMAPTKMT2AALDH1A1 | |
| SCHEMBL633994 | 0.77 | ALDH1A1 (0.68) | MEN1CYP3A4MAPTCYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275593-A1 | 3 Substituted N-(aryl- or heteroaryl)-pyrazolo[1,5-a]pyrimidines as Kinase Inhibitors | NOVARTIS AG | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275593-A1 | 3 Substituted N-(aryl- or heteroaryl)-pyrazolo[1,5-a]pyrimidines as Kinase Inhibitors | TIE1, TEK, MATK | MEN1 1920/4885LMNA 2608/4885CYP1A2 1967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.