Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10744688 | 0.82 | SLC6A3 (0.42) | PKMNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL27794344 | 0.81 | KMT2A (0.37) | NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL19718384 | 0.79 | — | — | |
| SCHEMBL2593156 | 0.78 | — | — | |
| SCHEMBL7618093 | 0.74 | SLC6A3 (0.40) | ERBB2EPHA2KDREPHB4HDAC1 | |
| SCHEMBL15348516 | 0.74 | F2 (0.37) | PKMNPC1RAB9AHDAC1HDAC6 | |
| SCHEMBL855235 | 0.74 | — | — | |
| SCHEMBL15110978 | 0.74 | — | — | |
| SCHEMBL791669 | 0.74 | — | — | |
| SCHEMBL21962502 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622490-B2 | especially for multi-drug resistant strains | TIBOTEC PHARMACEUTICALS, LTD. (IE) | 2009-11-24 | — | — | US | disclosed |