Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | PI4KA | P42356 | 1/20 | 0.48 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3960593 | 0.84 | CYP19A1 (0.37) | PIK3CAPI4KAPI4KBPRMT1CDC25A | |
| SCHEMBL13629649 | 0.84 | SREBF2 (0.42) | PRMT1CDC25ACDC25BGFERCYP19A1 | |
| SCHEMBL3647330 | 0.82 | CDC25A (0.38) | PIK3CAPI4KAPI4KBPRMT1CDC25A | |
| SCHEMBL13615799 | 0.81 | PDE10A (0.38) | PIK3CAPI4KAPI4KBPRMT1CDC25A | |
| SCHEMBL13057201 | 0.81 | PIK3CD (0.51) | PIK3CAPI4KAPI4KBPRMT1CDC25A | |
| SCHEMBL20390797 | 0.80 | MEN1 (0.50) | PIK3CACDC25ACDC25BCYP19A1MEN1 | |
| SCHEMBL20390796 | 0.77 | CDC25A (0.40) | PRMT1CDC25ACDC25BCYP19A1MEN1 | |
| SCHEMBL4308509 | 0.76 | CYP2E1 (0.46) | PIK3CAPI4KAPI4KBCDC25ACDC25B | |
| SCHEMBL4308505 | 0.76 | CDC25A (0.39) | PRMT1CDC25ACDC25BCYP19A1MEN1 | |
| SCHEMBL12680158 | 0.76 | CDC25A (0.34) | PIK3CAPI4KAPI4KBPRMT1CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203435-B1 | 6, 11-BRIDGED BIARYL MACROLIDES | ENANTA PHARM INC (US) | 2018-07-18 | — | — | EP | disclosed |
| US-20090281293-A1 | PROCESSES FOR THE PREPARATION OF 2 FLUORO 6-11 BICYCLIC ERYTHROMYCIN DERIVATIVES | ENANTA PHARMACEUTICALS, INC. | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281293-A1 | PROCESSES FOR THE PREPARATION OF 2 FLUORO 6-11 BICYCLIC ERYTHROMYCIN DERIVATIVES | CYP2F1, CYP2B6, CYP4F11 | PIK3CA 2823/4885PI4KA 3579/4885PI4KB 3623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.