Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14010813 | 0.84 | — | — | |
| SCHEMBL8402970 | 0.84 | ALDH1A1 (0.51) | GAAMAPTALDH1A1CYP2D6TSHR | |
| SCHEMBL13033057 | 0.82 | ATM (0.41) | GAAALDH1A1TSHRALOX15HSD17B10 | |
| SCHEMBL12337282 | 0.81 | KMT2A (0.49) | MAPTALDH1A1CYP2D6CYP1A2KMT2A | |
| SCHEMBL26075032 | 0.80 | CYP2C19 (0.55) | ALDH1A1CYP2D6TSHRCYP1A2HSD17B10 | |
| SCHEMBL14590566 | 0.80 | ALDH1A1 (0.51) | GAAMAPTALDH1A1CYP2D6TSHR | |
| SCHEMBL24260095 | 0.79 | TSHR (0.46) | GAAMAPTALDH1A1CYP2D6TSHR | |
| SCHEMBL772825 | 0.79 | MAPT (0.43) | GAAMAPTALDH1A1CYP2D6TSHR | |
| SCHEMBL12226350 | 0.79 | GAA (0.47) | GAAMAPTALDH1A1TSHRALOX15 | |
| SCHEMBL26510147 | 0.79 | GAA (0.47) | GAAMAPTALDH1A1TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622487-B2 | Piperidine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |
| US-7622487-B2 | Piperidine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |