Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.59 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.57 |
| ▸ | RBP4 | P02753 | 1/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.52 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.52 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.52 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.51 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13744784 | 0.85 | L3MBTL1 (0.73) | L3MBTL1EPHX2RIPK1RBP4CHRNB2 | |
| SCHEMBL22972208 | 0.83 | L3MBTL1 (0.75) | L3MBTL1EPHX2RIPK1RBP4CHRNB2 | |
| SCHEMBL7943306 | 0.82 | L3MBTL1 (1.00) | L3MBTL1EPHX2RBP4CHRNB2CHRNB4 | |
| SCHEMBL16003044 | 0.81 | EPHX2 (0.68) | L3MBTL1EPHX2RIPK1RBP4CHRNB2 | |
| SCHEMBL28448703 | 0.81 | L3MBTL1 (0.62) | L3MBTL1EPHX2RIPK1RBP4CHRNB2 | |
| SCHEMBL29500884 | 0.80 | MEN1 (0.57) | L3MBTL1EPHX2RIPK1RBP4CHRNB2 | |
| SCHEMBL21061661 | 0.80 | MEN1 (0.57) | L3MBTL1EPHX2RIPK1RBP4CHRNB2 | |
| SCHEMBL14197785 | 0.79 | L3MBTL1 (0.64) | L3MBTL1EPHX2RIPK1RBP4CHRNB2 | |
| SCHEMBL28467307 | 0.79 | L3MBTL1 (0.69) | L3MBTL1EPHX2RIPK1RBP4CHRNB2 | |
| SCHEMBL2224365 | 0.79 | L3MBTL1 (0.69) | L3MBTL1EPHX2RIPK1RBP4CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3456711-A1 | CASPASE INHIBITOR AND PHARMACEUTICAL COMPOSITION, USE AND THERAPEUTIC METHOD THEREOF | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2019-03-20 | — | — | EP | disclosed |
| US-7622487-B2 | Piperidine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |
| US-7622487-B2 | Piperidine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |