Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20821228 | 0.84 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1KDM4EPKMMAPT | |
| SCHEMBL6219127 | 0.83 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1KDM4EPKMGAA | |
| SCHEMBL13629917 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2TERTALDH1A1KDM4EPKM | |
| SCHEMBL28164677 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2TERTALDH1A1KDM4EPKM | |
| SCHEMBL14268127 | 0.80 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1MAPTKMT2ARAB9A | |
| SCHEMBL21983188 | 0.80 | ALDH1A1 (0.40) | SMN1; SMN2TERTALDH1A1KDM4EMAPT | |
| SCHEMBL14621507 | 0.80 | HSD17B10 (0.45) | SMN1; SMN2TERTALDH1A1KDM4EGAA | |
| SCHEMBL12156678 | 0.79 | SMN1; SMN2 (0.67) | SMN1; SMN2KMT2A | |
| SCHEMBL16076280 | 0.79 | TDP1 (0.47) | SMN1; SMN2ALDH1A1KDM4EMAPTGAA | |
| SCHEMBL19268642 | 0.79 | TDP1 (0.47) | SMN1; SMN2ALDH1A1KDM4EMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622487-B2 | Piperidine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |
| US-7622487-B2 | Piperidine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |