Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.85 |
| ▸ | DRD3 | P35462 | 9/20 | 0.85 |
| ▸ | HTR2A | P28223 | 5/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4493642 | 1.00 | DRD2 (0.85) | DRD2DRD3HTR2A | |
| SCHEMBL13629947 | 0.93 | DRD3 (0.73) | DRD2DRD3HTR2A | |
| SCHEMBL4482964 | 0.93 | DRD3 (0.73) | DRD2DRD3HTR2A | |
| SCHEMBL4480329 | 0.90 | DRD3 (0.69) | DRD2DRD3HTR2A | |
| SCHEMBL13630398 | 0.90 | DRD3 (0.69) | DRD2DRD3HTR2A | |
| SCHEMBL4480402 | 0.90 | DRD3 (0.69) | DRD2DRD3HTR2A | |
| SCHEMBL13630511 | 0.90 | DRD3 (0.69) | DRD2DRD3HTR2A | |
| SCHEMBL6680587 | 0.90 | DRD2 (0.84) | DRD2DRD3 | |
| SCHEMBL6680591 | 0.90 | DRD2 (0.84) | DRD2DRD3 | |
| SCHEMBL4495986 | 0.90 | DRD2 (0.79) | DRD2DRD3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090286801-A1 | CARBONYLATED (AZA) CYCLOHEXANES AS DOPAMINE D3 RECEPTOR LIGANDS | BIOPROJET (FR) | 2009-11-19 | — | — | US | disclosed |
| US-20090286801-A1 | CARBONYLATED (AZA) CYCLOHEXANES AS DOPAMINE D3 RECEPTOR LIGANDS | BIOPROJET (FR) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286801-A1 | CARBONYLATED (AZA) CYCLOHEXANES AS DOPAMINE D3 RECEPTOR LIGANDS | DRD3, TACR2, TACR1 | DRD2 4/4885DRD3 1/4885HTR2A 225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.