Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2435983 | 0.89 | NR1I2 (0.35) | S1PR1SPR | |
| SCHEMBL2435980 | 0.89 | NR1I2 (0.35) | S1PR1SPR | |
| SCHEMBL2432964 | 0.88 | KDM4E (0.37) | — | |
| SCHEMBL13630669 | 0.88 | EZH2 (0.35) | SPR | |
| SCHEMBL2432963 | 0.88 | KDM4E (0.37) | — | |
| SCHEMBL13630801 | 0.87 | S1PR1 (0.33) | S1PR1 | |
| SCHEMBL13630644 | 0.84 | ACKR3 (0.37) | S1PR1 | |
| SCHEMBL13630690 | 0.79 | GRM4 (0.33) | — | |
| SCHEMBL2431148 | 0.77 | EZH2 (0.35) | — | |
| SCHEMBL2431146 | 0.77 | EZH2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090274655-A1 | 2-CARBOXY THIOPHENE DERIVATIVES AS ANTI VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090274655-A1 | 2-CARBOXY THIOPHENE DERIVATIVES AS ANTI VIRAL AGENTS | EIF2AK2, HAVCR2, GTF3C2 | S1PR1 2888/4885SPR 1374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.