SCHEMBL136308

SCHEMBL136308

CCOc1cc(-c2ccc(N)c(OCC)c2)ccc1N

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 1.00
HSD17B10 Q99714 4/20 1.00
MAPT P10636 3/20 1.00
MEN1 O00255 3/20 1.00
KMT2A Q03164 3/20 1.00
POLB P06746 2/20 1.00
KDM4E B2RXH2 2/20 1.00
HPGD P15428 1/20 1.00
MAPK1 P28482 1/20 1.00
L3MBTL1 Q9Y468 1/20 1.00
TDP1 Q9NUW8 4/20 0.59
CYP3A4 P08684 2/20 0.59
TSHR P16473 2/20 0.59
NPC1 O15118 2/20 0.46
USP2 O75604 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
ROCK2 O75116 1/20 0.45
TP53 P04637 1/20 0.45
CREBBP Q92793 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2779956 0.92 ALDH1A1 (0.85) ALDH1A1HSD17B10MAPTMEN1KMT2A
SCHEMBL26381942 0.92 ALDH1A1 (0.85) ALDH1A1HSD17B10MAPTMEN1KMT2A
SCHEMBL3781455 0.91 ALDH1A1 (0.82) ALDH1A1HSD17B10MAPTMEN1KMT2A
SCHEMBL3783982 0.88 ALDH1A1 (0.77) ALDH1A1HSD17B10MAPTMEN1KMT2A
SCHEMBL310905 0.88 ALDH1A1 (0.77) ALDH1A1HSD17B10MAPTMEN1KMT2A
SCHEMBL6753624 0.85 ALDH1A1 (0.73) ALDH1A1HSD17B10MAPTMEN1KMT2A
SCHEMBL3789210 0.84 ALDH1A1 (0.71) ALDH1A1HSD17B10MAPTMEN1KMT2A
SCHEMBL9069655 0.83 ALDH1A1 (0.71) ALDH1A1HSD17B10MAPTMEN1KMT2A
SCHEMBL9621972 0.83 ALDH1A1 (0.70) ALDH1A1HSD17B10MAPTMEN1KMT2A
SCHEMBL2026347 0.83 ALDH1A1 (0.70) ALDH1A1HSD17B10MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104246914-B Insulated electric conductor and its manufacture method 住友电气工业株式会社 2017-07-07 CN disclosed
EP-1479713-B1 POLYAMIDE-IMIDE RESIN, FLEXIBLE METAL-CLAD LAMINATE, AND FLEXIBLE PRINTED WIRING BOARD TOYO BOSEKI (JP) 2015-04-01 EP disclosed
CN-104246914-A Insulated electric wire and method for manufacturing same SUMITOMO ELECTRIC INDUSTRIES 2014-12-24 CN disclosed
CN-102639640-B Urethane modified polyimide based flame retardant resin composition TOYO BOSEKI 2014-06-11 CN disclosed
US-20140017398-A1 MANUFACTURING METHOD OF LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL ALIGNMENT ELEMENT CHI MEI CORPORATION (TW) 2014-01-16 US disclosed
US-20130310572-A1 LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL ALIGNMENT ELEMENT USING THE SAME CHI MEI CORPORATION (TW) 2013-11-21 US disclosed
CN-102639640-A Urethane modified polyimide based flame retardant resin composition TOYO BOSEKI 2012-08-15 CN disclosed
US-8222365-B2 Polyamideimide resin, as well as a colorless and transparent flexible metal-clad laminate and circuit board obtained therefrom TOYO BOSEKI KABUSHIKI KAISHA (JP) 2012-07-17 US disclosed
US-20120094015-A1 Liquid crystal alignment agent and liquid crystal alignment film formed therefore and manufacturing method thereof CHI-MEI CORPORATION 2012-04-19 US disclosed
US-20120058262-A1 Liquid crystal alignment agent and liquid crystal alignment film formed therefore and manufacturing method thereof CHI-MEI CORPORATION 2012-03-08 US disclosed
US-5160504-A Colorfastness to rubbing and light, metal-tanned leather ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 1992-11-03 US disclosed
US-5095100-A Metal complex dyes and preparation thereof ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 1992-03-10 US disclosed
WO-1991013941-A1 WATER-INSOLUBLE AZO DYES, THEIR MANUFACTURE AND USE HOECHST AKTIENGESELLSCHAFT (DE) 1991-09-19 WO disclosed
EP-0211272-A2 AZO compound and colored composition containing same DAINICHISEIKA COLOR & CHEMICALS MFG. CO. LTD. (JP) 1987-02-25 EP disclosed
US-4496481-A REACTING AMINE, COUPLING COMPONENT AND NITRITE;PIGMENTS AND DISPERSE DYES CIBA-GEIGY CORPORATION (US) 1985-01-29 US disclosed
US-4260540-A SPIN DYEING POLYACRYLONITRILE BAYER AKTIENGESELLSCHAFT (DE) 1981-04-07 US disclosed
US-4246401-A Axomethine pigments BAYER AKTIENGESELLSCHAFT (DE) 1981-01-20 US disclosed
US-4242258-A TETRAKISAZO, BLACK HOECHST AKTIENGESELLSCHAFT (DE) 1980-12-30 US disclosed
US-4225489-A Heterocyclic azo dyes and pigments containing 4-quinazolinone moieties BAYER AKTIENGESELLSCHAFT (DE) 1980-09-30 US disclosed
US-4133780-A Polyurethane foams prepared from condensation products of amines, epihalohydrins and alkylene oxides BASF WYANDOTTE CORPORATION (US) 1979-01-09 US disclosed