Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL671182 | 0.83 | ALDH1A1 (0.41) | ALDH1A1CYP2E1HTT | |
| SCHEMBL4344584 | 0.83 | ALDH1A1 (0.41) | ALDH1A1CYP2E1HTT | |
| SCHEMBL13630694 | 0.82 | CYP2E1 (0.33) | CYP2E1 | |
| SCHEMBL13630643 | 0.81 | — | — | |
| SCHEMBL13630959 | 0.81 | ALDH1A1 (0.43) | ALDH1A1HTT | |
| SCHEMBL13852269 | 0.77 | — | — | |
| SCHEMBL4840200 | 0.74 | ALDH1A1 (0.34) | ALDH1A1CYP2E1HTT | |
| SCHEMBL4840195 | 0.74 | ALDH1A1 (0.34) | ALDH1A1CYP2E1HTT | |
| SCHEMBL13630804 | 0.72 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL14048964 | 0.72 | NR1I2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090274655-A1 | 2-CARBOXY THIOPHENE DERIVATIVES AS ANTI VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090274655-A1 | 2-CARBOXY THIOPHENE DERIVATIVES AS ANTI VIRAL AGENTS | EIF2AK2, HAVCR2, GTF3C2 | ALDH1A1 860/4885CYP2E1 118/4885HTT 3128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.