Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | SUV39H2 | Q9H5I1 | 3/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13434374 | 0.93 | SCN9A (0.40) | SCN9ASUV39H2PDE4BNSD2EHMT2 | |
| SCHEMBL13434517 | 0.89 | SCN9A (0.37) | SCN9ASUV39H2PDE4BNSD2EHMT2 | |
| SCHEMBL13434506 | 0.89 | SCN9A (0.38) | SCN9APDE4BERBB2EPHA2EPHB4 | |
| SCHEMBL13434503 | 0.87 | SCN9A (0.39) | SCN9ASUV39H2PDE4BALOX5APFEN1 | |
| SCHEMBL13434487 | 0.85 | PDE4B (0.41) | SCN9APDE4BUSP30 | |
| SCHEMBL13630941 | 0.85 | SCN9A (0.40) | SCN9APDE4BALOX5APFEN1USP30 | |
| SCHEMBL3487836 | 0.85 | KMT2A (0.35) | PDE4B | |
| SCHEMBL13434355 | 0.84 | REN (0.40) | SCN9APDE4BALOX5APFEN1NSD2 | |
| SCHEMBL3487524 | 0.82 | REN (0.39) | — | |
| SCHEMBL3488763 | 0.79 | KMT2A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119702-A1 | AMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2009-11-18 | — | — | EP | disclosed |