Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | REN | P00797 | 19/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13434352 | 1.00 | PDE4B (0.50) | PDE4BRENHTR1AADRA1DHTR2A | |
| SCHEMBL13631035 | 0.94 | PDE4B (0.45) | PDE4BRENHTR1AADRA1DHTR2A | |
| SCHEMBL13461244 | 0.94 | REN (0.47) | PDE4BRENHTR1AADRA1DHTR2A | |
| SCHEMBL13434590 | 0.94 | PDE4B (0.45) | PDE4BRENHTR1AADRA1DHTR2A | |
| SCHEMBL13434387 | 0.94 | REN (0.47) | PDE4BRENHTR1AADRA1DHTR2A | |
| SCHEMBL13434386 | 0.94 | PDE4B (0.45) | PDE4BRENHTR1AADRA1DHTR2A | |
| SCHEMBL13434593 | 0.94 | REN (0.47) | PDE4BRENHTR1AADRA1DHTR2A | |
| SCHEMBL13434595 | 0.93 | REN (0.45) | PDE4BRENHTR1AADRA1DHTR2A | |
| SCHEMBL13434388 | 0.93 | REN (0.45) | PDE4BRENHTR1AADRA1DHTR2A | |
| SCHEMBL13434381 | 0.92 | REN (0.43) | PDE4BRENHTR1AADRA1DHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119702-A1 | AMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2009-11-18 | — | — | EP | disclosed |