Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 7/20 | 0.41 |
| ▸ | KAT7 | O95251 | 1/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 5/20 | 0.37 |
| ▸ | BCHE | P06276 | 4/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13434478 | 0.91 | USP30 (0.40) | USP30KAT7KAT8ACKR3HPGDS | |
| SCHEMBL13630930 | 0.87 | SCN9A (0.40) | USP30KAT7SCN9AHTR6BCHE | |
| SCHEMBL13630941 | 0.87 | SCN9A (0.40) | USP30KAT7SCN9AHTR6BCHE | |
| SCHEMBL13631124 | 0.85 | SCN9A (0.38) | USP30KAT7SCN9AHTR6BCHE | |
| SCHEMBL13630929 | 0.84 | SCN9A (0.38) | USP30KAT7SCN9AHTR6BCHE | |
| SCHEMBL13434468 | 0.84 | REN (0.42) | USP30SCN9A | |
| SCHEMBL3488508 | 0.82 | KDM4E (0.37) | — | |
| SCHEMBL13434355 | 0.82 | REN (0.40) | USP30KAT7KAT8SCN9AAPLNR | |
| SCHEMBL13434461 | 0.81 | USP30 (0.49) | USP30KAT7KAT8ACKR3HPGDS | |
| SCHEMBL13434374 | 0.81 | SCN9A (0.40) | USP30KAT7SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119702-A1 | AMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2009-11-18 | — | — | EP | disclosed |