Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.56 |
| ▸ | HTR1A | P08908 | 2/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.55 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.55 |
| ▸ | HTR2B | P41595 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13461340 | 1.00 | REN (0.56) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL13434558 | 1.00 | REN (0.56) | RENHTR1AADRA1DHTR2AADRA1A | |
| Hydrochloric Acid SCHEMBL3487493 | 0.99 | REN (0.55) | RENHTR1AADRA1DHTR2AADRA1A | |
| Hydrochloric Acid SCHEMBL3488711 | 0.89 | REN (0.55) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL13434563 | 0.88 | REN (0.57) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL13461341 | 0.88 | REN (0.57) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL13434584 | 0.87 | REN (0.53) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL13461321 | 0.87 | REN (0.53) | RENHTR1AADRA1DHTR2AADRA1A | |
| Hydrochloric Acid SCHEMBL3487792 | 0.87 | REN (0.57) | RENHTR1AADRA1DHTR2AADRA1A | |
| SCHEMBL13434588 | 0.87 | REN (0.54) | RENHTR1AADRA1DHTR2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119702-A1 | AMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2009-11-18 | — | — | EP | disclosed |