Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.34 |
| ▸ | APP | P05067 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9922651 | 0.85 | P2RY12 (0.42) | P2RY12FBP1MEN1KMT2ALMNA | |
| SCHEMBL14200788 | 0.77 | CYP19A1 (0.46) | P2RY12FBP1MEN1KMT2ALMNA | |
| SCHEMBL9923034 | 0.76 | P2RY12 (0.46) | P2RY12FBP1MEN1KMT2ALMNA | |
| SCHEMBL13633800 | 0.76 | KDR (0.38) | P2RY12FBP1MEN1KMT2ALMNA | |
| SCHEMBL9922561 | 0.75 | P2RY12 (0.44) | P2RY12FBP1MEN1KMT2ALMNA | |
| SCHEMBL1548736 | 0.75 | P2RY12 (0.49) | P2RY12FBP1MEN1KMT2ALMNA | |
| SCHEMBL9922956 | 0.73 | MEN1 (0.41) | P2RY12FBP1MEN1KMT2ALMNA | |
| SCHEMBL9922556 | 0.73 | P2RY12 (0.43) | P2RY12FBP1MEN1KMT2ALMNA | |
| SCHEMBL12706443 | 0.72 | P2RY12 (0.51) | P2RY12FBP1MEN1KMT2ALMNA | |
| SCHEMBL9922563 | 0.71 | P2RY12 (0.49) | P2RY12FBP1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622474-B2 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |
| US-7622474-B2 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |