Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9922205 | 0.90 | KCNQ3 (0.38) | KCNQ3KCNQ2CA12CA1CA2 | |
| SCHEMBL9922395 | 0.89 | P2RY12 (0.36) | KCNQ3KCNQ2CA12CA1CA2 | |
| SCHEMBL9922196 | 0.88 | KCNH2 (0.34) | KCNQ3KCNQ2 | |
| SCHEMBL9922979 | 0.88 | ADRA2A (0.35) | KCNQ3KCNQ2 | |
| SCHEMBL9922408 | 0.88 | CA12 (0.33) | KCNQ3KCNQ2CA12CA1CA2 | |
| SCHEMBL12161598 | 0.88 | CA12 (0.36) | KCNQ3KCNQ2CA12CA1CA2 | |
| SCHEMBL9922394 | 0.87 | KCNH2 (0.36) | — | |
| SCHEMBL9922177 | 0.87 | P2RY12 (0.32) | KCNQ3KCNQ2CA12CA1CA2 | |
| SCHEMBL9922178 | 0.87 | KCNQ3 (0.35) | KCNQ3KCNQ2CA12CA1CA2 | |
| SCHEMBL9922213 | 0.86 | CA12 (0.36) | KCNQ3KCNQ2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622474-B2 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |
| US-7622474-B2 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |