Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 7/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12161305 | 0.96 | P2RY12 (0.44) | P2RY12FBP1MAPTKDM4EMEN1 | |
| SCHEMBL12161297 | 0.92 | P2RY12 (0.43) | P2RY12FBP1MAPTKDM4EMEN1 | |
| SCHEMBL9922729 | 0.89 | P2RY12 (0.47) | P2RY12FBP1MAPTKDM4EMEN1 | |
| SCHEMBL12161362 | 0.87 | FBP1 (0.39) | P2RY12FBP1MAPTKDM4EMEN1 | |
| SCHEMBL12161392 | 0.87 | P2RY12 (0.40) | P2RY12FBP1MAPTKDM4EMEN1 | |
| SCHEMBL9922687 | 0.86 | P2RY12 (0.47) | P2RY12FBP1MAPTKDM4EMEN1 | |
| SCHEMBL12161331 | 0.85 | P2RY12 (0.43) | P2RY12FBP1MAPTKDM4EMEN1 | |
| SCHEMBL9922095 | 0.85 | P2RY12 (0.48) | P2RY12FBP1MAPTMEN1KMT2A | |
| SCHEMBL9922705 | 0.83 | P2RY12 (0.48) | P2RY12FBP1MAPTKDM4EMEN1 | |
| SCHEMBL12177642 | 0.83 | P2RY12 (0.47) | P2RY12FBP1MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622474-B2 | Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-11-24 | — | — | US | disclosed |