Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | OGA | O60502 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3544311 | 0.80 | L3MBTL1 (1.00) | L3MBTL1ALDH1A1NPC1SMN1; SMN2PKM | |
| SCHEMBL12402370 | 0.76 | L3MBTL1 (0.67) | L3MBTL1ALDH1A1NPC1SMN1; SMN2PKM | |
| SCHEMBL29135323 | 0.76 | L3MBTL1 (0.67) | L3MBTL1ALDH1A1NPC1SMN1; SMN2PKM | |
| SCHEMBL2077603 | 0.74 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1NPC1SMN1; SMN2PKM | |
| SCHEMBL3435748 | 0.74 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1NPC1SMN1; SMN2PKM | |
| SCHEMBL10279631 | 0.74 | OGA (0.48) | SMN1; SMN2RAB9ATP53OGACTSB | |
| SCHEMBL3550329 | 0.73 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1NPC1SMN1; SMN2PKM | |
| SCHEMBL15269069 | 0.72 | L3MBTL1 (0.60) | L3MBTL1ALDH1A1NPC1SMN1; SMN2PKM | |
| SCHEMBL22136195 | 0.71 | PARP1 (0.58) | L3MBTL1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL13162278 | 0.71 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1NPC1SMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |