Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 4/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29921251 | 1.00 | PDK1 (0.41) | PDK1PDK2PDK3PRMT5KDM4E | |
| SCHEMBL30354026 | 0.86 | PDK1 (0.39) | PDK1PDK2PDK3KDM4ECA12 | |
| SCHEMBL17572003 | 0.84 | PDK1 (0.42) | PDK1PDK2PDK3PRMT5L3MBTL1 | |
| SCHEMBL17893278 | 0.84 | PDK1 (0.42) | PDK1PDK2PDK3PRMT5L3MBTL1 | |
| SCHEMBL17572807 | 0.84 | PDK1 (0.42) | PDK1PDK2PDK3PRMT5L3MBTL1 | |
| SCHEMBL15731644 | 0.84 | PDK1 (0.42) | PDK1PDK2PDK3PRMT5L3MBTL1 | |
| SCHEMBL13162310 | 0.81 | PDK1 (0.61) | PDK1PDK2PDK3KDM4EL3MBTL1 | |
| SCHEMBL21655140 | 0.81 | PDK1 (0.47) | PDK1PDK2PDK3PRMT5L3MBTL1 | |
| SCHEMBL30732668 | 0.79 | PDK1 (0.38) | PDK1PDK2PDK3KDM4EL3MBTL1 | |
| SCHEMBL19480263 | 0.79 | PDK1 (0.39) | PDK1PDK2PDK3PRMT5L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |