Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | CHUK | O15111 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634260 | 0.82 | IKBKB (0.47) | HRH3SLC6A4SLC6A2SLC6A3CHRM2 | |
| SCHEMBL13162815 | 0.82 | IKBKB (0.47) | HRH3SLC6A4SLC6A2SLC6A3CHRM2 | |
| SCHEMBL18112746 | 0.80 | GRIN2B (0.44) | HRH3GRIN2BPDE5APDE4APDE4B | |
| SCHEMBL13163123 | 0.80 | SLC6A2 (0.50) | SLC6A4SLC6A2SLC6A3HTR3AKCNH2 | |
| SCHEMBL16053711 | 0.78 | IRAK4 (0.32) | SLC6A4IRAK4MKNK1 | |
| SCHEMBL4958459 | 0.77 | MKNK1 (0.39) | SLC6A4SLC6A2SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL6648395 | 0.77 | HRH3 (0.44) | HRH3GRIN2B | |
| Hydrochloric Acid SCHEMBL8435746 | 0.76 | MKNK1 (0.39) | SLC6A4SLC6A2SLC6A3CHRNB2CHRNA4 | |
| SCHEMBL15129025 | 0.75 | MAPK8 (0.46) | HRH3GRIN2B | |
| SCHEMBL2299359 | 0.71 | TDP1 (0.52) | SLC6A4SLC6A2SLC6A3HTR3AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |