Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.47 |
| ▸ | CHUK | O15111 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.44 |
| ▸ | EED | O75530 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | SYK | P43405 | 2/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162815 | 1.00 | IKBKB (0.47) | IKBKBCHUKCHRNB2CHRNA4ROCK2 | |
| SCHEMBL13634315 | 0.82 | HRH3 (0.40) | IKBKBCHUKCHRNB2CHRNA4SLC6A2 | |
| SCHEMBL6648395 | 0.80 | HRH3 (0.44) | HRH3 | |
| SCHEMBL13163123 | 0.79 | SLC6A2 (0.50) | IKBKBCHUKSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL15129025 | 0.78 | MAPK8 (0.46) | HRH3 | |
| SCHEMBL27158000 | 0.78 | CHRNB2 (0.65) | IKBKBCHUKCHRNB2CHRNA4ROCK2 | |
| SCHEMBL14334552 | 0.78 | IRAK4 (0.46) | IKBKBCHUKCHRNB2CHRNA4ROCK2 | |
| Hydrochloric Acid SCHEMBL27157904 | 0.77 | CHRNB2 (0.50) | IKBKBCHUKCHRNB2CHRNA4ROCK2 | |
| SCHEMBL2267290 | 0.77 | SLC6A2 (0.57) | IKBKBCHUKCHRNB2CHRNA4EED | |
| SCHEMBL3444195 | 0.77 | SLC6A2 (0.57) | IKBKBCHUKCHRNB2CHRNA4EED |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |