Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.45 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | OGA | O60502 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13163986 | 0.93 | HRH3 (0.43) | HRH3PTGER1SCDOGALDHA | |
| SCHEMBL13162288 | 0.88 | HRH3 (0.61) | HRH3SCDOGALMNAMEN1 | |
| SCHEMBL13163987 | 0.87 | PTGER1 (0.40) | HRH3PTGER1OGALDHALMNA | |
| SCHEMBL13162807 | 0.87 | HRH3 (0.48) | HRH3PTGER1SCDOGALDHA | |
| SCHEMBL13162769 | 0.86 | HRH3 (0.47) | HRH3PTGER1SCDOGALDHA | |
| SCHEMBL3435877 | 0.85 | HRH3 (0.52) | HRH3PTGER1SCDOGALDHA | |
| SCHEMBL2079085 | 0.83 | HRH3 (0.54) | HRH3PTGER1SCDOGALDHA | |
| SCHEMBL2079022 | 0.82 | MAPT (0.51) | LMNAMEN1ALDH1A1POLBBLM | |
| SCHEMBL13163984 | 0.81 | HRH3 (0.56) | HRH3SCDOGALMNAMEN1 | |
| SCHEMBL13634311 | 0.81 | HRH3 (0.47) | HRH3PTGER1SCDOGALDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206707-B1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2014-07-23 | — | — | EP | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |