Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634246 | 0.81 | OGA (0.36) | EPHX2 | |
| SCHEMBL13634366 | 0.80 | PDE9A (0.30) | — | |
| SCHEMBL15888657 | 0.79 | HCRTR1 (0.41) | GPR119OPRM1OPRK1 | |
| SCHEMBL13634325 | 0.79 | ACACB (0.35) | — | |
| SCHEMBL13270669 | 0.78 | — | — | |
| SCHEMBL13162352 | 0.78 | EPHX2 (0.36) | GPR119EPHX2OPRM1OPRK1KCNH2 | |
| SCHEMBL13270665 | 0.78 | — | — | |
| SCHEMBL13634422 | 0.76 | SLC6A2 (0.32) | GPR119EPHX2SLC6A2SLC6A3OPRK1 | |
| SCHEMBL13634417 | 0.71 | HRH4 (0.31) | — | |
| SCHEMBL13634333 | 0.71 | HRH4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |