Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2J2 | P51589 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 3/20 | 0.34 |
| ▸ | DCK | P27707 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634325 | 0.93 | ACACB (0.35) | OGA | |
| SCHEMBL13634416 | 0.87 | KDM4E (0.34) | SCDDCK | |
| SCHEMBL13634366 | 0.87 | PDE9A (0.30) | — | |
| SCHEMBL13634245 | 0.86 | PDE3B (0.41) | EPHX2RETSCD | |
| SCHEMBL13634333 | 0.82 | HRH4 (0.31) | — | |
| SCHEMBL13634417 | 0.82 | HRH4 (0.31) | — | |
| SCHEMBL13634319 | 0.82 | NAAA (0.48) | EPHX2CYP2C9RET | |
| SCHEMBL13634397 | 0.81 | GPR119 (0.31) | EPHX2 | |
| SCHEMBL13634302 | 0.79 | PDE3B (0.47) | EPHX2RET | |
| SCHEMBL15888554 | 0.78 | HCRTR1 (0.44) | EPHX2CYP2C9CYP2J2CYP2C19RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |