Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | GPR6 | P46095 | 10/20 | 0.38 |
| ▸ | PAICS | P22234 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634511 | 0.90 | NAMPT (0.37) | ALDH1A1GPR6PAICSFGFR1NAMPT | |
| SCHEMBL13634510 | 0.90 | NAMPT (0.37) | ALDH1A1GPR6PAICSFGFR1NAMPT | |
| SCHEMBL13634580 | 0.89 | GPR6 (0.36) | GPR6PAICSFGFR1MALT1 | |
| SCHEMBL13638814 | 0.89 | PDE10A (0.41) | ALDH1A1GPR6NAMPTJAK3 | |
| SCHEMBL13634570 | 0.88 | GPR6 (0.40) | ALDH1A1GPR6ACACBFGFR1 | |
| SCHEMBL13634512 | 0.88 | SCD (0.39) | GPR6PAICSFGFR1MALT1 | |
| SCHEMBL13634571 | 0.88 | GPR6 (0.34) | GPR6PAICSACACBFGFR1IDO1 | |
| SCHEMBL13638874 | 0.86 | NAMPT (0.36) | GPR6PAICSFGFR1NAMPT | |
| SCHEMBL13634676 | 0.85 | GPR6 (0.42) | GPR6PAICSNAMPT | |
| SCHEMBL13634835 | 0.85 | PIM1 (0.42) | ALDH1A1GPR6PAICS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |